unusual presentation of gestational trophoblastic neoplasm: report of two cases
نویسندگان
چکیده
abstract: gestational trophoblastic neoplasm (gtn) is among rare human tumors which can be observed with widespread metastasis. two young patients with emergent neurologic symptoms with no gynecological problems are presented in this report. gtn was later diagnosed in both cases with brain metastasis. the first case: a 22 years old patient, admitted to the infectious disease ward, with probable diagnosis of encephalitis. after brain ct scan and measurement of β human chorionic gonadotropin (βhcg), gtn with brain metastasis was confirmed. the second case: a 33 years old patient who underwent craniotomy due to hemorrhagic brain tumor in neurosurgery department. brain metastatic gtn was confirmed by histological examinations. both cases received multiagent chemotherapy concurrent with whole brain irradiation of 3000 cgy in 10 fractions (f) within a period of 2 weeks, and chemotherapy was continued for additional course. the patients were both well after about 22 months. diagnosis of gtn should be considered in any woman of reproductive age.
منابع مشابه
Unusual presentation of gestational trophoblastic neoplasm: Report of two cases
Abstract: Gestational Trophoblastic Neoplasm (GTN) is among rare human tumors which can be observed with widespread metastasis. Two young patients with emergent neurologic symptoms with no gynecological problems are presented in this report. GTN was later diagnosed in both cases with brain metastasis. The first case: A 22 years old patient, admitted to the infectious disease ward, with probab...
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چکیده ندارد.
15 صفحه اولPlacental Site Trophoblastic Tumor: Clinical and Pathological Report of Two Cases
Placental site trophoblastic tumor (PSTT) is the rare variant of gestational trophoblastic diseases (GTD), which differs histologically and immunologically from GTD. Diagnosis of PSTT is often difficult and delayed. In most cases, diagnosis is not possible until the surgery is performed. The most therapeutic choice is hysterectomy and it is usually successful. Here we report two cases of PST...
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عنوان ژورنال:
iranian journal of radiation researchجلد ۳، شماره ۴، صفحات ۱۹۹-۲۰۲
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